RNAi
September 2, 2019
ORION-11: A Landmark Event for RNAi Therapeutics
The results from the ORION-11 Phase 3 study of inclisiran, presented earlier today at the European Society of Cardiology meeting represent a landmark event...
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May 12, 2019
What is RNAi and How Do RNAi Therapeutics Work?
What is RNAi? This video explains how Alnylam is leading the translation of RNAi to create an entirely new class of innovative medicines to treat disease.
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September 10, 2018
A Triumph of Perseverance Over Interference [Nature Biotechnology]
The following Editorial appeared in Nature Biotechnology (36,775 2018) on September 6, 2018...
"A triumph of perseverance over interference"...
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August 11, 2018
New Kind of Drug, Silencing Genes, Gets FDA Approval [Wall Street Journal]
The following article appeared in The Wall Street Journal on August 10, 2018...
"New Kind of Drug, Silencing Genes, Gets FDA Approval"...
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April 30, 2018
Hunting for Targets: Bringing RNAi to Humans
Evolution is a powerful force, and Mother Nature is often a great source of inspiration for drug hunters like me. If you look at the history of successful...
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April 30, 2018
Building to Scale: Raising RNAi Therapeutics From Infancy
When I joined Alnylam in 2004, one of our early challenges was figuring out how to manufacture and deliver RNAi therapeutics for our clinical trials. The...
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February 28, 2018
Harnessing the Power of RNAi™: Pushing Through the Challenges and Setbacks
I am an organic chemist, and what keeps me going after 3 decades working in the field of oligonucleotides is transforming complex chemistry into medicines...
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February 28, 2018
RNAi Therapeutics: From Eureka! Moment to a Potential New Class of Medicines
How far science and technology have come! At Alnylam, we believe we’re on the verge of a landmark moment in medicine and I can’t help but express my...
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