/* Revslider fonts */

@font-face {
    font-family: 'revicons';
    src: url('./fonts/revicons.eot?5510888');
    src: url('./fonts/revicons.eot?5510888#iefix') format('embedded-opentype'), url('./fonts/revicons.woff?5510888') format('woff'), url('./fonts/revicons.ttf?5510888') format('truetype'), url('./fonts/revicons.svg?5510888#revicons') format('svg');
    font-weight: normal;
    font-style: normal;
}

html,
body,
* {
    box-sizing: border-box;
}


.inline {
  display: flex;
  align-items: center;
}
sub, sup {
	position: relative;
	font-size: 0.75em !important;
	line-height: 0 !important;
	vertical-align: baseline !important;
}
hr {
	margin-top: 20px;
	margin-bottom: 20px;
	border: 0;
	border-top: 1px solid #eeeeee;
	opacity: 1;
}
.single .article_body  ol ol, .single .article_body  ul ul {
	padding: 0 0 0 15px;
}
/* Toolbar for logged in users */

.visually-hidden {
    display: none;
}
.related .relatedlink {
  font-weight: 900 !important;
}
#toolbar-bar {
    z-index: 9999;
}

#toolbar-bar .toolbar-menu a {
    font-weight: 600;
    color: #434343 !important;
}

#toolbar-bar .toolbar-tab>a {
    color: #fff !important;
}

body.toolbar-fixed.user-logged-in {
    padding-top: 78px;
}

body.toolbar-fixed.user-logged-in header.sticky.sticky_animate {
    top: 78px;
}

body.toolbar-tray-open.toolbar-vertical.toolbar-fixed {
    margin-left: 0px;
}


/* End of Toolbar for logged in users */

.container_inner {
    position: relative;
}

a.search_button {
    line-height: 1 !important;
}

#banner,
#hero {
    z-index: 1;
    position: relative;
}

#hero {
    max-height: 384px;
    overflow: hidden;
}

#hero img {
    width: 100%;
    object-fit: cover;
}

#content_inner {
    max-width: 1170px;
    margin: 0 auto;
    margin-top: -30px;
    padding: 50px 0px 64px 0px;
    background-color: #fff;
    z-index: 2;
    position: relative;
	overflow-anchor: none;
}
body:not(.page-node-type-article) #content_inner{
    margin-top: 0px;
  
}
h2.page_title {
    font-size: 45px;
    line-height: 1.1em;
    color: #00254b;
    text-align: center;
    text-transform: initial;
    letter-spacing: 1px;
    padding-bottom: 32px;
}

h4.page_subline {
    font-size: 35px;
    font-weight: 300;
    color: #00254b;
    text-align: center;
    margin-top: 10px;
    margin-bottom: 40px;
    line-height: 1.1em;
    padding-bottom: 10px;
}

.cta_widget {
    display: flex;
    justify-content: space-between;
    color: #fff;
}

.cta_widget .text {
    display: flex;
    align-self: center;
    height: fit-content;
}
.cta_widget .text * {
height: fit-content;
}

.cta_widget .text p {
    max-width: 300px;
    margin: 0px;
    color: #fff;
}

.cta_widget .text h2 {
    margin-right: 30px;
    padding: 0px;
}

.cta_widget .qbutton {
    /*min-width: 160px;*/
    text-align: center;
    height: 100%;
    display: table-cell;
}


/* Custom Checkbox */

.slim_checkbox {
    float: left;
    position: relative;
    width: 16px;
    height: 16px;
    border: 1px solid #6B6B6E;
    margin-right: 7px;
    overflow: hidden;
}

.slim_checkbox.checked {
    border-color: #FF9900;
}
#content_inner .related{
margin-top:40px;
}
.single .article_body .tags {
  margin-bottom: 0;
}
.single .article_body .tags p {
	margin-bottom: 0;
}
.slim_checkbox.checked+span.text {
    color: #FF9900;
}

.slim_checkbox input {
    opacity: 0;
    cursor: pointer;
    z-index: 5;
    width: 100%;
    height: 100%;
    display: block;
    position: absolute;
    top: 0;
    left: 0;
    min-width: 16px;
    min-height: 16px;
    margin: 0;
}

.slim_checkbox span {
    display: none;
    justify-content: center;
    align-items: center;
    width: 16px;
    height: 16px;
}

.slim_checkbox.checked span {
    display: flex;
}


/* End of Custom Checkbox */


/* Revolution Slider */

.tparrows:before {
    color: #036 !important;
}

.tp-bullets .tp-bullet {
    /*height: 3px !important;
  width: 50px !important;
  border-radius: 0 !important;*/
    width: 9px !important;
    height: 9px !important;
    background-color: #999999 !important;
    cursor: pointer;
    margin-top: 10px;
}

.tp-bullets .tp-bullet.selected {
    background-color: #ff9900 !important;
}

.tp-bullets .tp-bullet-title {
    display: none;
}


/* Lity Popup */

.lity-close {
    display: none;
}


/* Front Page */


/* Filter Area Styles */

#cats_wrapper {
    border-bottom: 1px solid #D8D8D8;
    text-align: center;
    padding-left: 75px;
    padding-right: 75px;
}

#cats a {
    font-size: 18px;
    font-weight: 600;
    display: inline-block;
    border-bottom: 3px solid transparent;
    text-transform: uppercase;
}

#cats a.active,
#cats a:hover {
    color: #FF9900 !important;
}

#cats a.active {
    border-color: #FF9900;
}

#filter_wrapper {
    display: flex;
    justify-content: space-between;
    padding: 24px 0px;
    position: relative;
}

#filter_wrapper h4 {
    font-size: 23px;
    color: #6B6B6E;
    margin: 0;
}

#filter_wrapper #filter {
    display: flex;
    flex-direction: column;
    align-items: flex-end;
    margin-top: -30px;
}
.path-frontpage #filter_wrapper #filter {
	margin-top: 0;
}
#filter_wrapper #filter .handle {
	font-size: 23px;
	color: #6B6B6E !important;
	padding-right: 18px;
	background-image: url('../img/filter-arrow.svg');
	background-repeat: no-repeat;
	background-position: right bottom;
	margin-bottom: 10px;
}

#filter_wrapper #filter ul.active_filters {
    display: flex;
    flex-wrap: wrap;
    list-style: none;
    margin: 0;
}

#filter ul.active_filters li {
    display: flex;
    justify-content: space-between;
    align-items: center;
    font-size: 16px;
    font-weight: 500;
    color: #FF9900;
    border: 1px solid #FF9900;
    padding: 0px 16px;
    margin-right: 16px;
    margin-top: 15px;
}

#filter ul.active_filters li a {
    margin-left: 20px;
    color: #FF9900 !important;
    font-size: 25px;
}

#filter ul.active_filters li.action {
    justify-content: flex-end;
    border: none;
    padding-right: 0px;
    margin-right: 0px;
    display: none;
}

#filter_wrapper #filter ul.active_filters .action:first-child {
	display: none !important;
}

#filter ul.active_filters li.action a {
    color: #036 !important;
    font-size: 16px;
  font-weight:900;
}
#filter_wrapper h4 {
	font-weight: 400;
	line-height: 1.4em;
}
#filter_wrapper .filter_options {
    display: none;
    position: absolute;
    top: 60px;
    right: 0px;
    padding: 25px 20px;
    background-color: #fff;
    border: 1px solid #d8d8d8;
    min-width: 360px;
    z-index: 10;
}

#filter_wrapper .filter_options .main {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    border-bottom: 1px solid #d8d8d8;
}

.filter_options .main .filter_type h6 {
    font-size: 16px;
    color: #6B6B6E;
    font-weight: normal;
    line-height: 1;
    padding: 0px 50px 15px 8px;
    margin: 0;
    border-bottom: 1px solid #d8d8d8;
    text-transform: initial;
}

.filter_options .main .filter_type ul {
    list-style: none;
    margin: 0;
    padding: 15px 8px;
}

.filter_options .main .filter_type ul li {
    margin-bottom: 15px;
    line-height: 1;
}

.filter_options .main .filter_type ul li:hover .slim_checkbox {
    border-color: #FF9900;
}

.filter_options .main .filter_type ul li:hover span.text {
    color: #00254b;
}

.filter_options .main .filter_type ul label {
    font-size: 16px;
    font-weight: 400;
    cursor: pointer;
}

#filter_wrapper .filter_options .action {
    padding-top: 15px;
}

#filter_wrapper .filter_options .action a {
    line-height: 1;
    font-size: 17px;
    font-weight: 900;
    padding-left: 8px;
}

#filter_wrapper .filter_options .action a:after {
    display: none !important;
}
.search-results__rows small {
  font-weight:400;
}

/* End of Filter Area Styles */
.alnylam_search--main-wrap .search-results__row .search-result__description{
  font-weight:400 !important;
}

.alnylam_search--main-wrap .search-results__row .search-result__description a{
  font-weight:900 !important;
}
/* Articles Area */

.articles {
    padding: 0px;
}

.articles .view {
    margin-bottom: 32px;
    display: flex;
    justify-content: space-between;
}

.articles .view.view_2 {
    justify-content: flex-start;
}

.articles .article_wrapper {
    flex: 0 0 31.5%;
    position: relative;
    /*background-size: contain;*/
    background-size: 100% 100% !important;
}

.articles .view.view_2 .article_wrapper {
    margin-right: 32px;
}

.articles .article_wrapper.no_bg {
    background-color: rgba(153, 153, 153, 0.1);
}

.articles .article_wrapper:before {
    content: '';
    display: block;
    width: 100%;
    height: 100%;
    padding-top: 93.5%;
    box-sizing: border-box;
    background-image: linear-gradient(transparent, rgba(0, 0, 0, .6));
    transition: .3s;
}

.articles .article_wrapper:hover:before {
    background-image: linear-gradient(rgba(0, 0, 0, .6), rgba(0, 0, 0, .6));
}

.articles .article_wrapper.no_bg:before,
.articles .article_wrapper.media:before,
.articles .article_wrapper.press:before {
    background-color: transparent;
    background-image: none;
}

.articles .article {
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    padding: 24px;
    display: flex;
    flex-direction: column;
    justify-content: flex-end;
}

.articles .article .category {
    font-weight: bold;
    font-size: 12px;
    color: #ff9900;
    line-height: 1.5;
    margin-bottom: 8px;
    text-transform: uppercase;
    letter-spacing: 0.5px;
}

.articles .article .category.original {
    text-transform: none;
}

.articles .article .excerpt {
    font-size: 23px;
    line-height: 24px;
    color: #fff;
}

.articles .no_bg .article .excerpt {
    color: #6B6B6E;
}

.articles .article .default_img {
    background-repeat: no-repeat;
    background-size: contain;
    width: 144px;
    height: 144px;
    position: absolute;
    top: 40px;
    left: 50%;
    transform: translateX(-50%);
    z-index: -1;
}

.articles .large .article .default_img {
    width: 288px;
    height: 288px;
    top: 128px;
}

.articles .article .play_btn {
    background-color: #036;
    background-image: url(../img/play-btn.png);
    background-repeat: no-repeat;
    background-position: 29px 22px;
    background-size: 20px auto;
    border-radius: 50%;
    width: 72px;
    height: 72px;
    position: absolute;
    top: 50%;
    left: 50%;
    padding: 0px;
    transform: translate(-50%, -50%);
    transition: .3s;
}

.articles .article:hover .play_btn {
    background-color: #00254b;
}

.articles .article_wrapper.large {
    flex: 0 0 65.75%;
}

.articles .article_wrapper.large .article {
    padding-bottom: 48px;
}

.articles .article_wrapper.large .excerpt {
    font-size: 35px;
    line-height: 40px;
}

.articles .masonry .dual {
    flex: 0 0 31.5%;
}

.articles .masonry .dual .article_wrapper:first-child {
    margin-bottom: 32px;
}

.articles .dual .static .article {
    justify-content: center;
    align-items: center;
    text-align: center;
}

.articles .dual .static .category {
    font-weight: 600;
    font-size: 20px;
    color: #fff;
    padding-bottom: 15px;
    margin-bottom: 0px;
}

.articles .dual .static .divider {
    margin-bottom: 15px;
    border-top: 1px solid #ccc;
    width: 92px;
    height: 1px;
}

.articles .dual .static.media .divider {
    border-color: #00254b;
}

.articles .dual .static .desc {
    font-size: 20px;
    color: #fff;
    max-width: 170px;
}

.articles .dual .article_wrapper.press {
    background: #003366;
}
.articles .dual .article_wrapper.media {
    background: #0099cc;
}

.load_more {
    text-align: center;
}

.load_more button {
    color: #00254b;
    height: auto;
    line-height: 47px;
    padding: 0 29px;
    background-color: transparent;
    border: 2px solid #b9d9eb;
    font-size: 16px;
    font-weight: 600;
}

.load_more button:hover {
    color: #fff;
    background-color: #00254b;
}


/* End of Articles Area */


/* Single Article Page with sidebar */

#content_inner .single {
    margin-left: 80px;
    margin-right: 60px;
    display: flex;
    justify-content: space-between;
}

.single .article_body {
    flex: 1 0 100%;
    position: relative;
}

#featured .article_body h2.page_title {
    margin-right: 120px;
}

.single.sidebar .article_body {
    flex: 0 0 670px;
}

.single .share {
    margin-bottom: 59px;
}

.single .ncom .share {
    margin-left: 30px;
}

.single .share h4 {
    font-size: 17px;
    color: #333;
    font-weight: 600;
    line-height: 22px;
    padding: 0px;
}

.single .share .social_links a {
    margin-right: 12px;
    font-size: 17px;
}

.single .share .social_links a:last-child {
    margin-right: 0px;
}

.single .article_body .share {
    position: absolute;
    top: 0;
    right: 0;
    margin-bottom: 0px;
    margin-left: 0px;
}

.article_body .share-mobile {
    position: relative !important;
    display: flex;
    justify-content: flex-end;
    margin-bottom: 20px !important;
}

.article_body .share-mobile h4 {
    margin-right: 20px;
}

.single .article_body h2.page_title {
	font-weight: bold !important;
	font-size: 35px !important;
	color: #00254b;
	line-height: 40px !important;
	letter-spacing: -0.08px;
	text-align: left !important;
}
.single .article_body p {
	font-size: 17px;
	color: #333;
	margin-bottom: 24px;
	line-height: 24px;
	font-weight: 400;
}
.single .article_body .image span, 
.single .article_body .video span {
	font-size: 17px;
	color: #fff;
  font-weight: 400;
	background-color: #00254b;
	padding: 11px 50px;
	display: flex;
	justify-content: center;
	align-items: center;
}
h2.page_title {
	text-transform: none !important;
	font-size: 35px !important;
	text-align: left !important;
	line-height: 1.1em !important;
}
.single .article_body .subline p {
    font-size: 20px !important;
    color: #333;
    line-height: 32px;
    margin-bottom: 24px;
}
.single .video-wrapper {
	padding: 0 !important;
}
.single .article_body .date {
    font-size: 17px;
    font-weight: normal;
    color: #00254b;
    margin: 0;
}

.single .article_body .author {
    padding-left: 85px;
    min-height: 72px;
    display: flex;
    position: relative;
    flex-direction: column;
    justify-content: center;
    margin-top: 24px;
    margin-bottom: 31px;
}

.single .article_body .author img {
    position: absolute;
    top: 0px;
    left: 0px;
    border-radius: 50%;
    width: 72px;
    height: 72px;
}

.single .article_body .author h4 {
    font-size: 17px;
    font-weight: 900;
    line-height: 25px;
    padding: 0px;
}

.single .article_body .author .name {
    color: #00254b;
}

.single .article_body .author .role {
    color: #333;
}

.single .article_body p.mobile-eyebrow {
	font-size: 17px;
	color: #333;
	margin-bottom: 24px;
	line-height: 24px;
	font-weight: 400;
	margin-top: 0 !important;
}
.single .article_body p a {
  font-weight:900;
}
.single .article_body blockquote {
    margin: 10px 0px 35px 0px;
    padding: 0px 0px 0px 35px;
    background: url('/themes/custom/alnylam/img/quote.svg') no-repeat;
    font-size: 25px;
    color: #00254b;
    line-height: 32px;
  border-left: 4px solid transparent;
}

.single .article_body blockquote p {
	font-size: 25px;
	color: #00254b;
	line-height: 32px;
}


.single .article_body .date + a + p {
	font-size: 20px;
	font-weight: 400;
	font-stretch: normal;
	font-style: normal;
	line-height: 1.6;
	letter-spacing: normal;
	color: #333;
}
.single .article_body .date + a + p {
  font-size: 17px;
  line-height: 24px;
}


.related .relatedlink {
	text-transform: uppercase !important;
	letter-spacing: normal;
}
/* Media embed presets */

.single .article_body .image,
.single .article_body .video {
    margin-bottom: 30px;
    position: relative;
}

.single .article_body .video {
    cursor: pointer;
    border: 1px solid #b9d9eb;
}

.single .article_body .video .play_btn {
	background-color: transparent;
	background-image: url(../img/icons/play-btn.svg);
	background-image: url(../img/video-button.svg);
	background-repeat: no-repeat;
	background-position: center;
	background-size: 100%;
	border-radius: 50%;
	width: 64px;
	height: 64px;
	position: absolute;
	top: 50%;
	left: 50%;
	padding: 0px;
	transform: translate(-50%, -50%);
	transition: .3s;
}

.single .article_body .video:hover .play_btn {
    background-color: #ff9900;
    background-color: transparent;
}

.single .article_body .image img,
.single .article_body .video img {
    width: 100%;
    display: block;
}

.single .article_body .image span,
.single .article_body .video span {
    font-size: 17px;
    color: #fff;
    background-color: #00254b;
    padding: 11px 16px;
    display: flex;
    justify-content: center;
    align-items: center;
}

.single .article_body .pdf {
    margin-bottom: 30px;
}

.page-node-type-article .single .hr-red {
	font-size: 25px;
	padding-bottom: 16px;
	color: #303030;
}


/* End of Media embed presets */

.single .article_body .tags {
    margin-top: 10px;
    margin-bottom: 48px;
}

.single .article_body .tags a {
/*     text-decoration: 1px underline #b9d9eb; */
    text-underline-offset: 4px;
    margin-bottom: 3px;
    font-weight: 900;
}

.single .article_body .tags h4 {
    font-size: 25px;
    color: #00254b;
    text-transform: uppercase;
}

.single .article_body ul,
.single .article_body ol {
    list-style: none;
}
.slim_checkbox.checked + span.text{
  font-weight:400;
}
.single .article_body ul li {
    position: relative;
    padding-left: 30px;
    font-size: 17px;
    word-break: break-word;
    font-weight:400;
}
.single .article_body ul li a{
  font-weight:900;
}
.single .article_body ul li:before {
    content: '\2022';
    color: #ff9900;
    font-size: 24px;
    position: absolute;
    left: 10px;
    top: -2px;
}
.single .article_body ol li {
    counter-increment: li;
    position: relative;
    padding-left: 30px;
    font-size: 17px;
    word-break: break-word;
}

.single .article_body ol li:before {
    content: counter(li);
    color: #ff9900;
    font-weight: 500;
    position: absolute;
    left: 10px;
}

.single .sidebar {
    flex: 0 0 256px;
}

.single .sidebar .navigation .terms h4 {
    font-size: 23px;
    color: #6B6B6E;
    line-height: 30px;
    border-bottom: 1px solid #d8d8d8;
    margin-bottom: 20px;
  
  font-weight:300;
}

.single .sidebar .navigation .terms ul {
    list-style: none;
    margin: 0;
    padding: 0;
}

.single .sidebar .navigation .terms ul li a {
    line-height: 32px;
    font-size: 20px;
}

.single .sidebar .navigation .terms ul li.active a {
    color: #FF9900 !important;
    font-weight: 900;
}

#content_inner .related {
    display: block;
    margin-left: 80px;
    margin-right: 80px;
}
.single .article_body p a b {
  font-weight: 900;
}
#content_inner .related h5 {
    font-size: 25px;
    text-transform: uppercase;
    color: #00254b;
    margin-bottom: 30px;
}

#content_inner .related .articles .view {
    justify-content: flex-start;
}

#content_inner .related .articles .article_wrapper {
    flex: 0 0 33.3%;
    margin-right: 24px;
    max-width: calc(33.3% - 16px);
}

#content_inner .related .articles .article_wrapper:last-child {
    margin-right: 0px;
}


/* End of Single Article Page with sidebar */


/* Single Article in Taxonomy Page */

.taxonomy .article {
    padding: 0;
    margin-bottom: 40px;
}

.taxonomy .article img {
    width: 100%;
}

.taxonomy .article .image {
    position: relative;
}

.taxonomy .article .image .video {
    background: url('../img/play-button.svg') no-repeat;
    background-size: contain;
    width: 72px;
    height: 72px;
    position: absolute;
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
}

.taxonomy .article .date {
    font-size: 17px;
    font-weight: normal;
    color: #FF9900;
    margin-top: 32px;
    margin-bottom: 24px;
    display: block;
}

.taxonomy .article .subject {
    font-size: 23px;
    font-weight: 600;
    color: #00254b;
    line-height: 28px;
    margin-bottom: 8px;
    display: block;
}

.taxonomy .article .summary {
    font-size: 17px;
    margin-bottom: 16px;
    display: block;
}

.taxonomy .article a {
    font-size: 17px;
    font-weight: normal;
  font-weight: 900;
    display: block;
}


/* New Class of Medicine taxonomy */

.ncom_intro {
    padding-top: 40px;
    padding-bottom: 40px;
    border-bottom: 1px solid #d8d8d8;
}

.ncom_intro .video-wrapper {
	cursor: pointer;
	position: relative;
	max-height: unset;
}

.ncom_intro .image img {
    width: 100%;
}

.ncom_intro .image .play_btn {
    background-color: #ff9900;
    background-image: url(../img/play-btn.png);
    background-repeat: no-repeat;
    background-position: 29px 22px;
    background-size: 20px auto;
    border-radius: 50%;
    width: 72px;
    height: 72px;
    position: absolute;
    top: 50%;
    left: 50%;
    padding: 0px;
    transform: translate(-50%, -50%);
    transition: .3s;
}

.ncom_intro .image:hover .play_btn {
    background-color: #ff9900;
}

.ncom_intro .headline {
    margin-top: 20px;
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.ncom_intro .headline .subject {
    font-weight: 600;
    font-size: 23px;
    color: #00254b;
    white-space: nowrap;
}

.ncom_intro .headline .share {
    display: flex;
    justify-content: flex-end;
    width: 100%;
    margin: 0;
}

.ncom_intro p {
    margin-top: 10px;
    margin-bottom: 0px;
  font-weight:400;
}

.ncom_articles {
    margin-top: 40px;
    display: flex;
    flex-wrap: wrap;
}

.ncom_articles .article {
    flex: 0 0 50%;
    padding-bottom: 30px;
}

.ncom_articles .article:nth-child(odd) {
    padding-right: 15px;
}

.ncom_articles .article:nth-child(even) {
    padding-left: 15px;
}

.ncom_articles .article .media {
    position: relative;
    padding-top: 100%;
    background-size: 100% 100% !important;
}

.ncom_articles .article .no_bg {
    background-color: rgba(153, 153, 153, 0.1);
}

.ncom_articles .article .media .default_img {
    background-image: url('../img/magnifier.png');
    background-repeat: no-repeat;
    background-size: contain;
    width: 144px;
    height: 144px;
    position: absolute;
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
    z-index: -1;
}

.ncom_articles .article .media .play_btn {
    background-color: #ff9900;
    background-image: url(../img/play-btn.png);
    background-repeat: no-repeat;
    background-position: 29px 22px;
    background-size: 20px auto;
    border-radius: 50%;
    width: 72px;
    height: 72px;
    position: absolute;
    top: 50%;
    left: 50%;
    padding: 0px;
    transform: translate(-50%, -50%);
    transition: .3s;
}

.ncom_articles .article .media:hover .play_btn {
    background-color: #ff9900;
}

.ncom_articles .article h5 {
    font-weight: 600;
    font-size: 23px;
    color: #00254b;
    padding: 0px;
    margin-top: 10px;
    margin-bottom: 10px;
    line-height: 1.1em;
}

.ncom_articles .article p {
    font-size: 14px;
    margin-bottom: 15px;
   font-weight:400;
}

.ncom_articles .article > a {
	font-weight: 900;
	color: #036;
	font-size: 14px;
}

.single .sidebar .ncom_banner {
    padding: 30px 30px;
    max-width: 231px;
    background-color: #663366;
    text-align: center;
    color: #fff;
}
.single .sidebar p {
    color: #fff;
}

.single .sidebar .ncom_banner h5 {
    font-size: 23px;
    font-weight: 600;
    line-height: 28px;
    color: #fff;
    margin: 0;
    text-transform: uppercase;
}

.single .sidebar .ncom_banner .divider {
    width: 110px;
    border-top: 1px solid #fff;
    height: 1px;
    margin: 15px auto;
}

.single .sidebar .ncom_banner p {
    font-size: 17px;
    line-height: 24px;
    margin-bottom: 30px;
  font-weight: 400;
}

.single .sidebar .ncom_banner button {
    color: #fff;
    height: auto;
    line-height: 47px;
    padding: 0 29px;
    background-color: #036;
    border: none;
    font-size: 18px;
    font-weight: 400;
}


/* End of New Class of Medicine taxonomy */


/* User Page */

.user-login-form {
    text-align: center;
    margin-bottom: 20px;
}


/* End of User Page */


/* External Link Popup */

#external_popup {
    max-width: 800px;
    background-color: #fff;
    border: 5px solid #000;
    position: relative;
    padding: 70px 80px;
}

#external_popup .inner {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    text-align: center;
}

#external_popup .inner h3 {
    font-size: 20px;
    font-weight: bold;
    text-transform: none;
    margin-bottom: 20px;
}

#external_popup .inner p {
    font-size: 18px;
    color: #333;
    max-width: 100%;
}

#external_popup .inner a.confirm {
    margin-top: 40px;
    width: 240px;
    background-color: rgba(0, 153, 204, 1);
    border: none;
    color: #fff !important;
    font-size: 16px;
    font-weight: normal;
    line-height: 3;
    text-align: center;
    text-decoration: none;
}

#external_popup .inner button.close {
  border: none;
  position: absolute;
	top: -6px !important;
	right: -18px !important;
	background: url(/themes/custom/alnylam/img/video-close-button.svg) no-repeat 0px !important;
	width: 50px !important;
	height: 50px !important;
	opacity: 1;
}


.footnote p {
    font-size: 12px !important;
    padding-left: 6px;
}

.footnote p sup {
    top: 0px;
    left: -3px;
    margin-left: -3px;
}


/* End of External Link Popup */


/* Search Style By Effvision*/

.side_menu_button .search_button_btn {
    background-color: transparent;
    border: none;
    display: block !important;
    position: absolute;
    right: 0;
    top: 4px;
}

.side_menu_button .qode_icon_font_awesome.search-icon.fa.fa-search.mobile-view {
    margin-bottom: 10px !important;
}

.side_menu_button .search_button .elastic-search-input {
    border: none;
    max-width: 53px;
}



input.elastic-search-input:focus {
    outline: none !important;
}

@media (min-width:600px) {
    .side_menu_button .search_button .elastic-search-input {
        max-width: 118px;
        padding-right: 30px;
    }
}

@media (min-width:1000px) {
    .side_menu_button .search_button .elastic-search-input {
        padding-right: 0;
    }

    header.sticky .side_menu_button .search_button .elastic-search-input {
        max-width: 58px;
    }
}

@media only screen and (max-width: 767px) {
    header:not(.sticky) a.search_button span {
        display: none;
    }
    .side_menu_button .search_button_btn {
        background-color: transparent;
        border: none;
        display: block !important;
        position: absolute;
        right: 0;
        top: 2px;
    }
    header:not(.sticky) a.search_button {
        width: 80px;
        border-bottom: 1px solid #00254b;
        padding-bottom: 2px;
        display: block;
        padding-left: 3px;
    }
    .side_menu_button .search_button_btn {
        margin-right: 0 !important;
        padding-right: 0 !important;
    }
    header:not(.sticky) a .elastic-search-input {
        padding-bottom: 0px !important;
    }
}
@media only screen and (max-width: 767px) {
    #social_wrapper .q_social_icon_holder a {
        min-width: auto !important;
    }
}
@media(min-width:1000px) and (max-width:1050px) {
    .sticky .header_menu_bottom nav.main_menu>ul>li>a {
        margin: 0 13px !important;
    }
}
@media (min-width:1000px){
    #filter_wrapper {
        display: flex;
        justify-content: space-between;
    }
}



/**** for the Pager ********/
.pager {
	margin: 20px 0 0px 0;
	text-align: center;
}
.pagination.js-pager__items {
	display: inline-block;
	padding-left: 0 !important;
	margin: 20px 0 !important;
	border-radius: 4px;
	width: auto !important;
	list-style-position: inside;
	list-style: none;
}

.pagination li {
	margin: 0 11px 0 0;
	display: inline;
	text-align: center;
}
.pagination li a {
	position: relative;
	display: inline-block;
	width: 40px;
	height: 40px;
	margin: 0 11px 0 0;
	text-align: center;
	color: #337ab7;
	font-size: 18px;
	text-decoration: none;
	text-transform: uppercase;
	cursor: pointer;
	white-space: nowrap;
	border: 2px solid #e5e5e5;
	outline: 0;
	padding: 5px 5px;
	border: 2px solid #e5e5e5;
	font-size: 18px;
	cursor: pointer;
	border-radius: 6px;
	line-height: 23px;
}
.pagination li.is-active a{
    border-color: #f8f8f8;
    background-color: #f8f8f8 !important;
    color: #303030 !important;
}
@media (max-width:767px){
    .pagination li a {
        width: 32px;
        height: 32px;
        margin: 0 0px 0px 0;
        padding: 2px 0px;
        padding-right: 0px;
    }
}
.pagination li.page-item.disabled {
	display: inline-block;
	max-width: 13.5px;
}
.page-link:focus {
	box-shadow: none !important;
}
.pagination li.page-item.disabled .page-link {
	display: inline;
	background-color: #FFF;
	border: 0;
	padding: 0;
}
.main_menu {
	height: auto;
}
.path-frontpage h2.page_title::before {
    background-image: url(/themes/custom/alnylam/img/heading-news.png);
    background-size: 50px 30px;
    display: inline-block;
    width: 50px;
    height: 30px;
    content: "";
    margin-right: 16px;
}

.path-frontpage h2.page_title { font-size: 45px !important; }
 .open_search #search-input button {
  position: absolute;
  right: 0;
  top: 10px;
}
.path-frontpage #content_inner h2.page_title{
  text-align:center !important;
}
@media (max-width:991px) {
    .path-frontpage h2.page_title { 
    text-align: left;
    
    }
  #filter_wrapper{
		display:block;
	}
    #filter_wrapper .filter_options {
      top: 60px;
      width: 100%;
      max-width: 360px;
    }
    .path-frontpage h2.page_title { margin-left: 16px; margin-right: 16px; }
    .path-frontpage h2.page_title::before  {
        background: url(/themes/custom/alnylam/img/heading-news-mobile.png) 0 0  no-repeat;
        background-size: 14px 100%;
        width: 24px;
        height: .65em;
        content: "";
        margin-right: 0px;
        margin-left: -24px;
    }
  .mobile-menu-open ul li #language_selector_1 {
  display: flex;
  align-items: center;
  padding: 0 !important;
  justify-content: center;

}
  
.header_bottom {
  background-color: transparent !important;
}
.alnylam__basic-search-block #search-open-btn {
  margin: 0;
  padding: 0;
  width: 24px;
  position: relative;
  left: 0;
}
.header_bottom  #global_languages{
  width:24px;
}

.header_bottom {
  padding:0 !important;
}
  #language_selector_1 .open-lang {
  color: #fff !important;
}
  .content{
    margin-top:56px !important;
  }
  .header_bottom #global_languages {
  width: 24px;
  right: 24px;
}
.open_search .header_bottom {
  position: absolute;
  max-width: 100%;
  left: 28px !important;
  width: calc(100% - 44px);
}
  .open_search #search-input {
  width:100%;
}
  .open_search .alnylam__basic-search-block form {
  display: flex;
}
  .open_search .alnylam__basic-search-block .input-group input {
  max-width: 100% !important;
  font-size: 16px;
  border-radius: 0;
  border: 1px solid #ddd;
  height: 41px;
  padding: 15px 35px 15px 15px;
  color: #002855;
  letter-spacing: 0;
  font-weight: 500;
  margin-left: auto;
  display: block;
  box-shadow: none;
  width: 100%;
}
  .open_search #search-input {
  width: 100%;
  padding: 0;
  border: 0;
}
 .open_search  .header_menu_bottom_inner{
    width:100%;
  }
 .open_search #search-input button {
  position: absolute;
  right: 0;
  top: 10px;
}
  .open_search .alnylam__basic-search-block{
    width:100%;
  }
   .open_search .alnylam__basic-search-block #search-close-btn{
    margin:0;
    padding:0;
  }
}


#filter_wrapper .filter_options .action a {
	font-size: 17px;
	font-weight: 900;
	font-stretch: normal;
	font-style: normal;
	line-height: 1.41;
	letter-spacing: normal;
	color: #00254b;
	border-bottom: solid 1.5px #b9d9eb;
	text-transform: uppercase;
	padding-left: 0;
	margin-left: 8px;
	transition: 0.3s all;
}
@media(min-width:1000px){
  .alnylam__basic-search-block{
    height:24px;
  }
.alnylam__basic-search-block .input-group {
  padding: 8px 5px;
  margin-top: -8px;
}
  .open_search #search-input button {
 
  top: 8px;
}
  .alnylam__basic-search-block #search-open-btn, .alnylam__basic-search-block #search-close-btn {
  margin-bottom: 5px;
}
}

/* selim edits  */
.single .article_body .author h4 {
	line-height: 24px !important;
}
.articles .article .play_btn {
    background-color: unset !important;
    background-image: url(../img/video-button.svg) !important;
    background-repeat: no-repeat;
    background-position: unset !important;
    background-size: unset !important;
    border-radius: 50%;
    width: 64px;
    height: 64px;
    position: absolute;
    top: 50%;
    left: 50%;
    padding: 0px;
    transform: translate(-50%, -50%);
    transition: .3s;
}
@media  (min-width: 768px) and (max-width: 1000px){
  .rev_slider_wrapper {
    height: 710px  !important;
  }
  .wrapper_inner #banner .tparrows.uranus.noSwipe {
  top: 88% !important;
}
  .rev_slider {
  height: 690px  !important;
}
    .media {
	    margin-top: unset;
    }
  .articles .grid .article_wrapper:nth-child(3) {
	    margin-top: 16px !important;
    }
  .articles .view {
	    margin-bottom: 16px !important;
    }
  .articles .masonry > .article_wrapper {
	    margin-top: 6px !important;
    }

}
.ncom_intro .headline .subject {
  line-height: 1.1em;
  padding-bottom: 10px;
}
@media  (max-width: 767px){
     .MsoNormal.susanne {
	    margin-bottom: 32px !important;
    }
  .ncom_intro .headline .subject {
    line-height: 1.4em;
    padding-bottom: 10px;
  }
}
/***End Selim Edit***/
.call_to_action {
	padding: 64px 24px !important;
}
.call_to_action .cta_widget .text {
	display: flex;
	align-self: center;
	height: fit-content;
	flex-direction: column;
}
.call_to_action .cta_widget .text p{
  max-width:100%;
  font-weight:400;
}
.call_to_action .cta_widget .text h2 {
	margin-bottom: 8px;
	font-size: 35px;
	font-weight: bold;
	font-stretch: normal;
	font-style: normal;
	line-height: 1.14;
}

@media  (max-width: 1000px){
  .call_to_action .container_inner {
    width: 100%;
  }
  .call_to_action {
    padding: 64px 32px !important;
  }
  footer .footer_top .container_inner .col .textwidget {
    flex-direction: row !important;
  }
  footer .footer_inner .footer_top {
    padding: 40px 32px 8px 32px !important;
  }
  
}
@media  (max-width: 767px){
  .call_to_action .cta_widget {
    display:block;
    text-align: left;
  }
  .call_to_action .cta_widget .text {
    margin-bottom: 32px;
  }
  .call_to_action .cta_widget .text h2{
    margin-bottom:16px;
  }
  .call_to_action .cta_widget .text p {
    max-width: 100%;
    margin-bottom: 0;
  }
  .call_to_action .cta_widget > div .qbutton.white.internal {
    display: block;
    margin-left: 0;
    transform: none;
  }
}

/* Maggi styles */

@media (max-width:991px){
  .path-frontpage h2.page_title {
  font-size: 32px !important;
  line-height: 1 !important;
}
  .path-frontpage .load_more{
    margin-top:32px;
  }
  .call_to_action_text .text p{
    line-height:1.4;
  }
}
@media (max-width:1000px){
  .custom-iframe{
   max-width: 100%;
    
  }
}
@media (max-width:767px){

  .custom-iframe iframe{
   max-width: 100%;
    height:90px;
  }
}
/*End Maggi Edits */




@media (min-width: 768px) and (max-width: 894px) {
  #cece-slide:nth-child(8) > .tp-parallax-wrap:nth-child(2) {
      top: 70px !important;
  }
  
  .custom-iframe iframe{
   max-width: 100%;
  }
}


div#cats a.internal:focus,
.slick-list a.internal:focus {
    outline: none;
    text-decoration: none;
}

.related .relatedlink, #content_inner .related h5, .single .article_body .tags h4 {
	padding-bottom: 10px;
}

.fa, .fa-brands, .fa-classic, .fa-regular, .fa-sharp, .fa-solid, .fab, .far, .fas {
	-moz-osx-font-smoothing: grayscale;
	-webkit-font-smoothing: antialiased;
	display: var(--fa-display,inline-block);
	font-style: normal;
	font-variant: normal;
	line-height: 1;
	text-rendering: auto;
}
.fa-brands, .fab {
	font-family: "Font Awesome 6 Brands";
}
.fa-x-twitter::before {
	content: "\e61b";
}
.single .share .social_links a {
	font-size: 17px;
}
.fa-envelope-o::before {
	content: "\f003";
}
.twitter.internal svg {
	max-width: 17px;
	max-height: 17px;
	fill: #00254b;
	margin-top: -3px !important;
	display: inline-block;
}

.twitter.internal:hover svg {
	fill: #f90 !important;
}

.article_body .date {
	padding-bottom: 16px;
}
.single .sidebar .ncom_banner h5 {
	padding-bottom: 10px;
}
.single .sidebar .navigation .terms h4 {
	padding-bottom: 10px;
}

.sidelink {
	margin-top: 50px;
	text-align: left;
}


.headline .social_links {
	display: flex;
	gap: 15px;
}
.headline .share .social_links a {
	margin-right: 0;
	font-size: 17px;
}
.headline .twitter.internal {
	min-width: 17px;
}

.path-user .form-item {
	text-align: left;
}
.path-user .form-actions #edit-submit {
	width: 100%;
	background: #00245b;
	border: 0 !important;
	padding: 6px 40px;
	font-size: 18px;
	font-weight: 600;
	color: #fff;
	height: auto;
	display: inline-block;
	text-transform: uppercase;
	text-decoration: none;
	line-height: 2em;
	transition: 0.3s all;
	border-radius: 6px;
}
.path-user  #block-alnylam-page-title{
  display: none;
}

.page-node-type-article .single .hr-red {
	padding-bottom: 16px;
	color: #303030;
}
.page-node-type-article .single  .hr-red {
  padding-bottom: 16px;
}
@media(min-width:768px){
  .page-node-type-article .single  .hr-red {
    font-size: 25px;
  }
}
@media(max-width:767px){
  .page-node-type-article .single  .hr-red {
    font-size: 20px;
  }
}